11/10/2023 0 Comments G3zed 12![]() Pricing models used by Goldman Sachs & Co. The estimated value of your notes at the time the terms of your notes are set on the trade date (as determined by reference to The notes are not bank deposits and are not insured by the Federal Deposit InsuranceĬorporation or any other governmental agency, nor are they obligations of, or guaranteed by, a bank. Any representation to the contrary is a criminal offense. ![]() Neither the Securities and Exchange Commission nor any other regulatory body hasĪpproved or disapproved of these securities or passed upon the accuracy or adequacy of this prospectus. Supplemental plan of distribution conflicts of interest on page PS-7. *The original issue price will be % for certain investors see Summary Information Key Terms LLC would initially buy or sell your notes, if it makes a market in the notes, see the following page. For a discussion of the estimated value and the price at which Goldman Sachs & Co. The estimated value of your notes at the time the terms of your notes are set on the trade date is expected to be between $920Īnd $970 per $1,000 face amount. You should read the disclosure herein to better understand the terms and risks of your investment, including the credit risk of GS Finance Corp. You will receive less than the face amount of your notes. Plus (ii) the product of (a) the sum of the index return plus 25% times (b) $1,000. If the index return is negative and is below -25% (the final index level is less than the initial index level by more than 25%), the sum of (i) $1,000 Initial index level, but not by more than 25%), $1,000 or If the index return is zero or negative but not below -25% (the final index level is equal to the initial index level or is less than the ![]() (b) the participation rate times (c) the index return If the index return is positive (the final index level is greater than the initial index level), the sum of (i) $1,000 plus (ii) the product of (a) $1,000 times At maturity, for each $1,000 face amount of your notes, you will receive an amount in cash equal to: To determine your payment at maturity, we willĬalculate the index return, which is the percentage increase or decrease in the final index level from the initial index level. You could lose a significant portion of the face amount of your notes. If the final index level declines by more than 25% from the initial index level, the return on your notes will be negative and willĮqual the index return plus 25%. If the final index level declines by up to 25% from the initial index level, you will receive Return on your notes will be positive and will equal the participation rate (expected to be between 1.06 and 1.16) times the index return. If the final index level on the determination date is greater than the initial index level (set on the trade date), the To be August 31, 2023) is based on the performance of the S&P 500 ® Index as measured from the trade date (expected to be August 28, 2018) to and including the determination date The amount that you will be paid on your notes on the stated maturity date (expected Leveraged Buffered S&P 500 ® Index-Linked Notes due This preliminary pricing supplement is not an offer to sell nor does it seek an offer to buy these securities in any jurisdiction where the offer or sale is not permitted. The information in this preliminary pricing supplement is not complete and
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11/10/2023 0 Comments Firewatch updates![]() Secrets and discoveries to be made over every hill.A tailor-made story: the choices you make shape the narrative and build relationships.A stunningly beautiful wilderness environment that expands as you explore.If you plan on playing with a younger gamer, that might be good to know going in. Provide the public a single source of incident. Firewatch is a first-person single-player mystery set in the Wyoming wilderness, where your only emotional lifeline is the person on the other end of a handheld radio. The web-based program provides information for wildland fire emergencies and prescribed fires, but can also be used for other natural disasters and emergency incidents such as earthquakes, floods, hurricanes, tornadoes, etc. But when something strange draws you out of your lookout tower and into the forest, you’ll explore a wild and unknown environment, facing questions and making choices that can build or destroy the only meaningful relationship you have.Ī Note: Firewatch is a video game about adults having adult conversations about adult things. InciWeb is an interagency all-risk incident information management system. Your supervisor Delilah is available to you at all times over a small, handheld radio-your only contact with the world you've left behind. An especially hot, dry summer has everyone on edge. Perched high atop a mountain, it’s your job to look for smoke and keep the wilderness safe. You are a man named Henry who has retreated from his messy life to work as a fire lookout in the Wyoming wilderness. The Northwest Large Fire map depicts large fires in Oregon and Washington reported to the NWCC and is updated daily throughout the fire season. ![]() Its popularity has surprised its founder, the software. So far, it’s been downloaded by a quarter of a million people. Updates Daily Weather Forecast Entertainment Contests & Promotions. The audio tour will include more than three hours of commentary from the developers and voice actors, almost 100 collectible audio tapes, displays of concept art, lighting demos, animation how-to. See current wildfires and wildfire perimeters near you using the Fire, Weather & Avalanche Center Wildfire Map. Perched high atop a mountain, it’s your job to look for smoke and keep the wilderness safe. Fire smoke blows north into C.O., causing more unhealthy air, while. Interactive real-time wildfire map for the United States, including California, Oregon, Washington, Idaho, Arizona, and others. The Washington DNR fire dashboard is active throughout the fire season and shows up. You are a man named Henry who has retreated from his messy life to work as a fire lookout in the Wyoming wilderness. Public Information Officer updates the public on the Chelan Fire Complex. About This Game Firewatch is a single-player first-person mystery set in the Wyoming wilderness. On June 1, 2022, Watch Duty expanded its reach to cover all of California. Firewatch is a single-player first-person mystery set in the Wyoming wilderness. 11/10/2023 0 Comments El camino ss 1987![]() An AM/FM radio is there for your listening pleasure, unless you'd rather listen to the sweet sound coming from the dual exhaust. This 1987 El Camino SS is optioned with AC, tilt, cruise, power steering, power brakes, power windows, and power door locks. Stock door panels, headliner, carpet, steering wheel and column shifter keep you in control and are in very good shape. The gauges are stock and very clean with no damage. Inside is in very nice condition the dash appears newer with no cracks and looks amazing. Hoses look newer and the temperature stays at a constant 190 while driving this fine example of American history. This El Camino has received a new exhaust, and a Delcotron alternator has been in stalled as they came from the factory. The engine compartment is all stock and very clean making it ready for the car shows or local cruise nights. This Super Sport is mostly original and its power plant is a traditional 5.0 V8 mated to a 3-Speed automatic which shifts smoothly as it should. There were 13,743 El Camino's produce in 1987 with only 861 SS's produced making this a rare collectible. We are pleased to offer this stunning 1987 Chevrolet El Camino SS This is 1 of only 861 Chevy El Camino SS that were produced for this year. Please visit for additional photos, information and a video. My preference is still the third-gen (’68-’72) but these down-sized fifth-gen editions are welcomed by many who prefer them over the unpopular, and rarely encountered, colonnade-inspired, fourth-gen (’73-’77) version.1987 Chevrolet El Camino SS, V8, AC, PW, PL, 1 of 861 Built, Rare !!! It’s not going to be a barn-burner like Caminos of yesteryear (150 net HP is adequate but that’s about it), but it has value in its own right. It has SS Sport Decor (RPO Z15), limited slip performance axle (RPO G 80 92), and heavy-duty suspension (RPO F41). So, there are some things here to consider besides the fact that this El Camino is one of the last. A/C is in the house but blowing cold is not currently in its bag of tricks. The carpet and door panels are following suit with a split dash cap the only interior component worthy of a demerit. The interior is surprisingly clean and presents well, I’m not certain about the originality of the seating upholstery (though it could be the optional cloth choice) but it reveals no degradation or excessive wear. This Camino has labored for 165K miles but the seller claims, “ Runs and drives well, handles nice“. Traditional small block V8s still provided forward motivation in ’87, and in this case, it’s a 150 net HP, 305 CI V8 engine working in concert with a four-speed automatic transmission. ![]() Also mentioned are the non-sagging doors, a problem that seems to dog two-door GM models from the ’60s forward. Other than a few scratches, the cargo bed is very sound-looking. That said, almost all of the trim is still in place, the body panels are straight, there’s no sign of rust, and the chrome-plated bumpers still shine. This example looks pretty good at first glance but close-ups show lots of flat, faded, and worn-through paint. To be specific, this El Camino is outfitted with the optional SS Sport Decor package and not the Choo Choo SS option which wears a Monte Carlo front clip. Calling Lakewood, Washington home, this end-of-the-line pickup is available, here on eBay for a no reserve bid of $4,550 with twenty-three bids tendered as of this writing. Even though the fifth generation El Camino (’78-’87) was little changed over its ten model-year run, let’s take a look at one of the last – I think there are many of us who wish it would return. And, the bowtie did drop out altogether from ’61 to ’63, but they owned the market from ’80 through ’87 as Ford bid adieu to the Ranchero in ’79. Ford beat Chevy to the punch by two years, introducing their Ute, the Ranchero, in ’57 with Chevrolet following suit in ’59. All good things come to an end and for Chevrolet’s half car/half truck, the El Camino, 1987 was it. 11/10/2023 0 Comments Island of lust updateThe onus remains on any person using material from court files to ensure that the intended use of that material does not breach any such order or provision. ![]() 40. An adult visual novel set in an alternate history of the Roman Empire. Lists for the Magistrates Courts are updated for the day at 6.45am and again at 8.45am (allowing for overnight arrests).Ĭlick on the refresh or reload button in your browser to view the most recent versions.Įvery effort has been made to comply with non-publication (suppression) orders or statutory provisions prohibiting publication that may apply to this information. Fixed Alissa not being strippable on Island-Fixed Fawn swimsuit being available before giving her one-Fixed Alissas name not showing in Island-Fixed chastity belt appearing over belly when pregnant. N khng phi l mt hn o bnh thng m l mt hn o kh c bit. Lists for the Supreme and District Courts are updated no later than 6.00pm for the following day. GVNVH18 Ni Dung Game: V ri bn pht hin ra mnh tri dt n mt hn o v danh ch ton l ph n. The Queensland law lists are updated daily. Supreme, District, Land and Magistrates Courts - civil and criminal
11/9/2023 0 Comments Games like fernbus simulator![]() Some customers also have physical boarding passes. Not every customer will have a digital boarding pass, though. You will then have the ability to scan tickets and even give discounts to customers. You can check-in by scanning the passengers with your mobile phone application. TOP/BEST ADULT VIDEO GAMES IN UNITED STATES OF AMERICA (USA) ![]() However, if a selected passenger is heading in the same direction, the game will let you explore that location by simply taking the passenger to their destination. In addition to driving to a destination to pick up your passengers at the stop, you’ll also have to worry about checking their boarding passes, putting their luggage in the vehicle and making sure you don’t accidentally get the wrong passengers on board. As you travel to each city, neighboring towns and surrounding locations are unlocked. You have to explore the game world to unlock all the cities and roads. Although its map works differently from other games, the cities on the map are unlocked in a similar way as the game progresses. You can even make your trips as long or short as you want. Unlike other bus and tractor simulators, Fernbus’ open world allows you to instantly set destinations and travel in any direction you want. ![]() Developed by TML-Studios, one of the well-known studios of the simulation world, the game was released on Steam on August 25, 2016. Fernbus Simulator Free Download GAMESPACK.NETįernbus Simulator Free Download GAMESPACK.NET Fernbus Simulator is a city bus simulator on European roads. 11/9/2023 0 Comments Kite pharma gilead good for kiteAdditionally, Gilead looks well-positioned to benefit a great deal from its partnership with Arcelix. The treatment is likely to be approved for use in many new indications. Yescarta’s sales are likely to continue to jump going forward. Very encouragingly, “78% of patients saw their tumors shrink or disappear due to the treatment, and 67% of patients showed a complete response, in which their tumors disappeared. In December, Yescarta was given to nine patients with blood cancers in their brain or spinal cords. In the second quarter, Yescarta’s sales jumped 29% versus the same period a year earlier to $380 million. Yescarrta was approved as a treatment for large B-cell lymphoma last year. This combats the 12% expected with standard of care, Gilead reported.Īnd in a Phase 3 trial earlier this year, Yescarta became “the first treatment in nearly 30 years to improve overall survival (OS) in relapsed/refractory large B-cell lymphoma,” BioSpace reported. Among the 62 patients who received Yescarta, 71% showed no signs of disease after three months. The company’s Yescarta therapy recently showed strong efficacy as a treatment for a type of blood cancer called large B-cell lymphoma. Gilead’s GILD Kite unit specializes in developing CAR T therapies. I view it as one of the best cancer drug stocks. I believe that Arcelix can become a pharmaceutical powerhouse. Furthermore, Arcelix is eligible to receive more money from Gilead if CART-ddBCMA is successful down the road. Under the deal, Arcelix received $225 million of cash from Gilead, while GILD bought $100 million of ACLX stock. Gilead GILD in December entered into a partnership with Arcelix two months after the strong data on CART-ddBCMA was unveiled. Further, 71% of the patients showed no signs of cancer after the study was complete. In a Phase 1 study of CART-ddBCMA, the condition of all 38 patients who received the treatment improved. It is a potential treatment for patients with certain kinds of a prevalent blood cancer known as multiple myeloma. Consequently, I view BMY as one of the best cancer drug stocks.Īrcelix ACLX developed a CAR T based treatment called CART-ddBCMA. I believe that the drug can ultimately become a huge blockbuster, significantly lifting Bristol-Myer’s financial results and BMY stock in the process. Last year, the Food and Drug Administration approved Breyzani as a treatment for “adult patients with large B-cell lymphoma.” This is another type of blood cancer.Īlso noteworthy is that BMY is testing the drug’s efficacy in many types of blood cancer. Still, given the fact that the patients had unsuccessfully tried so many other treatments in the past, I believe that the data was impressive. This wasn’t considered statistically significant. On a negative note, the overall response rate of the patients in the study, which represents the proportion of the participants whose condition improved, came in at 42.9%. Also worth noting is that the patients in the study had unsuccessfully tried many other drugs. ” None of the patients in the latter group “experienced disease progression or deaths by the data cutoff,” enabling the treatment to attain the study’s primary endpoint. “In the Phase 1/2 trial “Breyanzi eradicated signs of cancer in 18.4% of patients with heavily pretreated CLL or small lymphocytic lymphoma (SLL). According to Fierce Pharma, CLL is ” the most common form of leukemia. ![]() The therapy, Breyanzi, is a treatment for chronic lymphocytic leukemia (CLL). In January, Bristol Myers-Squibb BMY reported extremely positive data for one of its CAR T therapies. Here are three of the best cancer drug stocks that can advance tremendously, thanks in large part to the CAR T drugs that they’re developing. Finally, “After a one-time infusion, the CAR T cells can continue to multiply in the patient’s body after being administered,” Bristol-Myers Squibb BMY explained. ![]() In other words, CAR T produces treatments that are “personalized” to each patient. Moreover, unlike other cancer treatments, CAR T drugs enlist cells that come from the patients themselves in the cancer-fighting effort. This revolutionary techology has brought up some of the best cancer drug stocks we have ever seen. That’s because the treatments are specifically tailored to each patients’ T cells. One reason this type of therapy is so promising is that it produces treatments that work well within each patients’ body. CAR T also attacks other cells altered by tumors. Specifically, CAR T treatments work by reconfiguring T cells so that they attack proteins found on tumors. CAR T involves “reprogramming” patients’ T cells, which fight hostile cells within the body. ![]() Autologous chimeric antigen receptor T cell therapy is 0ne of the most promising, relatively new types of cancer treatments. 11/9/2023 0 Comments Liquid nail tape walmart![]() How do you keep your skin around your nails nice? ![]() Applying a thin layer of Vaseline on your cuticles or any skin surrounding your nails can help prevent polish from sticking to your skin. It also has soothing and healing properties, making it beneficial for dry or cracked cuticles. Vaseline can act as a barrier between the nail polish and your skin. Yes, you can use Vaseline around your nails when painting them. Can you put Vaseline around your nails when painting them? If this technique doesn't work for you, you can also use a thin brush to carefully apply the polish to the skin, ensuring a clean and neat manicure. The edge of the brush gives more precision. To avoid getting nail polish on your cuticles, you can try using the side of the brush to paint the nails near the cuticles. How do you paint your nails without flooding cuticles? By pushing back the cuticles, dead skin cells are cleared from the nail surface, allowing products like polish to adhere more easily and create a smoother finish. ![]() Nail artists push back cuticles to prepare the nails for better adhesion of products and to achieve longer-lasting results. Applying a thin layer of these products creates a barrier between the nail polish and your skin, making it easier to clean up any mistakes later. To protect the skin around your nails when painting, you can use products like vaseline, cuticle oil, or cream. What do you put on skin around nails when painting? After painting, you can easily wipe off the petroleum jelly or oil along with any polish mistakes. This will help to keep the polish from sticking to your skin. To prevent getting nail polish on your cuticles, you can create a barrier by applying petroleum jelly or cuticle oil around your nails and cuticles before painting. How do you prevent cuticles when painting your nails? 11/9/2023 0 Comments Et co2Once that has been done you can use an end tidal Co2 monitor as opposed to drawing multiple ABG's. It is best to get an ABG along side the end tidal to calculate the patients shunt. As stated before end tidal is slightly different. So the short answer is you are right about the ranges 35-45 but that is for actual PaCo2 drawn from an ABG. For a person with "normal" lungs the difference between end tidal and Paco2 can vary between 5-8mmHg depending on the book your reading. have values been revised since i last came out of school?Įnd tidal Co2 ranges vary slightly from actual PaCo2 and can be affected by many factors depending on the condition of the patients lungs. to make a long story short, i called the doctor after it was done (it was 30) and told him it was low, the patient may have alkalosis (from what i remember 15 years ago normal values are 35-45) and he told me that was perfectly normal. Have a quick question- The physician had requested an end tidal co2 on a trach and vent pediatric patient. And, as explained, the EtCO2 may not reflect the exact PaCO2. This would be repeat correlated periodically per facility protocol to make sure that the relationship between the two still stands.īeing able to determine alkalosis from an EtCO2 would be very difficult, since you have no pH or base value with which to balance the acid in the equation. However, because of mixing in the heart and syringe, PaCO 2 sampled at the radial artery is the spatial and. I’ve gotten several questions about the tCO2, pCO2, and which value is the one to use for blood gas analysis. tCO2 vs pCO2: Clearing up confusing terminology. Alveolar PCO 2 varies cyclically, being lowest at end-inspiration and highest at end-expiration. pCO2: Clearing Up Confusing Terminology Critical Care Veterinary Medicine. In order to help me guide my vent, I now know that I want to make adjustments so that my EtCO2 reads between 26 and 31. The net effect of these factors is to enable the terminal part of phase III to exceed mean PaC02, resulting in negative (a-ET)PC02.2. If the ABG comes back with a PaCO2 of 36, I now know that there is a difference of -4. We would hook up the EtCO2 and record the number (I'll say 32) at the time the ABG is drawn. The neurosurgeon may want EtCO2 monitoring and want to keep the PaCO2 between 30 and 35. ![]() Take, for example, a patient with massive head injury. ![]() In the case of EtCO2, what matters is how it reflects the PaCO2. Remember that all numbers in critical care must have a second number or observation to validate the first. EtCO2 values are looked at in relation to PaCO2 values. 11/9/2023 0 Comments Kleptomania symptoms and behaviorsrecurrent failure to resist impulses to steal objects) but do not provide details about severity levels and whether those can be meaningful in terms of treatment approaches. The DSM-5 criteria stipulate the minimal level of severity to meet diagnostic threshold (i.e. One approach to refining our treatment of kleptomania might be to better understand the range of illness severity and the clinical associations with severity. Thus, data are still lacking regarding optimal treatment options, duration and who with kleptomania would benefit more from medication or psychotherapy. To date, there have been no controlled clinical trials of any psychosocial interventions for kleptomania. By study endpoint, 66.7% of those assigned to naltrexone compared to 7.7% on placebo (p<.001) reported symptom remission. In that study, 25 subjects were randomized in a 1:1 fashion to either naltrexone or placebo for 8 weeks ( 9). There has been only one placebo-controlled trial of pharmacotherapy published for the treatment of kleptomania. Alternatively, kleptomania could be viewed as compulsive in that stealing without getting caught requires fore-planning and involves a complex rewarding behavior (as opposed to unplanned impulses) ( 6– 7).ĭespite being described in the medical literature for nearly two hundred years ( 8), kleptomania still remains poorly understood with limited data regarding its underlying pathophysiology and appropriate treatment choices. One neuroimaging study comparing individuals with kleptomania to healthy controls found decreased white matter microstructural integrity in inferior frontal brain regions consistent with difficulties in impulse control ( 5). Psychological testing has, in some studies, demonstrated greater cognitive impulsivity, larger deficits in inhibition, and greater sensation-seeking among individuals with kleptomania compared to controls ( 4). ![]() The behaviors that characterize kleptomania (e.g., urges to steal, inability to stop) might be conceptualized as impulsive in that they are often premature, poorly thought out, risky, and result in deleterious long-term outcomes. Although no large scale epidemiologic studies have been conducted to assess the prevalence of kleptomania in the general population, a survey of college students (N=791) found that 3 (0.38%) met criteria for kleptomania ( 3), suggesting that this disorder is relatively uncommon and/or that it is often concealed. The lifetime prevalence of shoplifting in the United States population was 11.3% ( 2). The National Epidemiologic Survey on Alcohol and Related Conditions (NESARC) assessed rates of stealing (not a formal diagnosis of kleptomania) among 43,000 adults. Kleptomania is characterized by repetitive stealing behavior precipitated by significant and uncontrollable urges to steal items not needed for their personal use ( 1). 11/9/2023 0 Comments Image bucket seats c10![]() These seats have the grommets just like the Sport X seats, but the Sport XR has black, unisuede wings like the Sport R. TMI Pro Classic Sport XR - THe Pro Classic Sport XR is essentially a combinaton of Sport R and Sport X.The color behind the grommet will match the color of the contrast stitching in standard configurations You have your choice of color of contrast stitching and your choice of grommet color. The pattern and materials are the same as the Sport, but the center is broken up with the grommets. TMI Pro Classic Sport X - TMI Pro Classic Sport X seats feature grommets down the center of the backrest and seat bottom.TMI Pro Classic Sport R - The Sport R has the same overall seat pattern as the Pro Classic Sport, but the Sport R features black unisuede "wings" to give your interior a little more modern appearance and to break up the seat, giving it a two-tone black appearance.TMI Pro Classic Sport - These bucket seats come standard with matte black vinyl and your choice of contrast stitching.What is the Difference Between the Pro Classic Styles? TMI Products has always taken pride in providing high quality products that give you custom upholstery shop quality, but at a price point for the automotive aftermarket. ![]() TMI started in the air-cooled VW market, making door panels and has since expanded into more than just door panels and much more than just air-cooled Volkswagens. Why TMI?TMI has been making interior for classic cars since 1982. |
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